SKU: 81431986833

TMG Pro Tablets - 1000 mg, 120 tablets

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Description

TMG Pro Tablets - 1000 mg, 120 tabletsA methyl donor that complements NMN and supports heart health and liver detoxification. Supports liver detoxification Supports cardiovascular health Promotes healthy homocysteine levels Supports cellular health View Certificate of Analysis Research Supported Benefits: Supports Cellular Health. TMG is an amino acid that supports the body's methylation processes. Methylation is essential for numerous important cellular functions, including cell

A methyl donor that complements NMN and supports heart health and liver detoxification.

  • Supports liver detoxification 
  • Supports cardiovascular health 
  • Promotes healthy homocysteine levels 
  • Supports cellular health 

View Certificate of Analysis

Research-Supported Benefits:

Supports Cellular Health. TMG is an amino acid that supports the body's methylation processes. Methylation is essential for numerous important cellular functions, including cell division, energy production and producing antioxidants to fight oxidative stress.1

Supports Detoxification. The donation of methyl groups by TMG is critical for healthy liver function and detoxification.1

Supports Cardiovascular Health. TMG may decrease blood levels of homocysteine, an amino acid that is linked to poor heart health and blood vessel damage when elevated.2

References:

1. Arumugam MK, Paal MC, Donohue TM Jr, Ganesan M, Osna NA, Kharbanda KK. Beneficial Effects of Betaine: A Comprehensive Review. Biology (Basel). 2021;10(6):456. Published 2021 May 22. doi:10.3390/biology10060456 

2. McRae MP. Betaine supplementation decreases plasma homocysteine in healthy adult participants: a meta-analysis. J Chiropr Med. 2013;12(1):20-25. doi:10.1016/j.jcm.2012.11.001 doi:10.1016/j.jcm.2012.11.001 

  • Trimethylglycine (TMG), also known as betaine anhydrous, is an amino acid that supports the body's methylation processes. 
  • Methylation is a fundamental biochemical process in which one carbon atom and three hydrogen atoms (CH3) are transferred from one molecule to another. 
  • Methylation is responsible for numerous important bodily functions, such as cell division, cellular energy production, clearing histamine, metabolism, DNA expression (epigenetics), forming neurotransmitters and producing free radical-scavenging antioxidants. 
  • Our bodies contain a “methyl pool” of CH3 that is available whenever needed. As long as we have enough methyl groups stored in the pool, methylation typically is not a problem. However, there are a couple of things that may contribute to the depletion of the body's methyl pool. 
  • MTHFR Variants - Methylenetetrahydrofolate reductase (MTHFR) is a gene with common mutations that can interfere with the methylation process, causing high levels of homocysteine (a known risk factor in heart health conditions) in the blood and low folate levels. Up to 40% of the population may have one or both genetic mutations. 
  • Aging and Epigenetics - Methylation of DNA plays a crucial role in epigenetics, switching different sequences of your genetic material on and off as needed. The body's methylation ability and subsequent DNA expression are known to decline with age. Anti-aging researchers think these changes in DNA expression may be a contributing factor to many age-related diseases. 
  • NMN Supplementation and Methylation Support. When taken as a supplement, NMN may require the use of methyl groups to help facilitate the conversion of NAD+ in your cells, thereby activating sirtuin genes and promoting longevity. Although there is currently no evidence suggesting NMN’s natural methylation process depletes the methyl pool, many top anti-aging experts suggest that safeguarding against methyl depletion may be a wise proactive step to augment your NMN intake. 
Supplement Facts
Serving Size: 1 Tablet
Servings Per Container: 120
Amount Per Serving %DV
Trimethylglycine (TMG) (Betaine Anhydrous) 1 g (1000 mg)
† Daily Value (DV) not established
REV.10.23
  • OTHER INGREDIENTS: Cellulose, stearic acid (vegetable source), croscarmellose sodium, magnesium stearate (vegetable source).
  • DOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.
  • SUGGESTED DAILY USE: Take 1-6 tablets daily, divided into 2 doses, or as recommended by your healthcare professional.
  • CAUTION: Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.
  • NOTE: Keep the bottle tightly closed at all times in between usage. Keep the freshness packet in bottle. This product is very sensitive to moisture/humidity which may affect product stability. Store in a cool dry place after opening. KEEP OUT OF REACH OF CHILDREN

Tablet Form. The tablet form of TMG Pro makes it easy to take.

Higher Dose. ProHealth’s TMG Pro contains 1,000 mg of TMG as Betaine Anhydrous, whereas other TMG supplements may contain just 750 mg.

Free of Unwanted Ingredients. TMG Pro doesn’t contain yeast, wheat, gluten, sugar, salt, dairy, eggs, peanuts, tree nuts, fish, shellfish, soy, corn, dye or preservatives.

Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.

Third-Party Tested in the USA. Every batch is third-party tested in USA laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.

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SKU: 81431986833

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Organized Life KC - Allison Denning
Belleville, US
★★★★★ 5
Truly refreshing right away
I am someone who gets a red face from even the most slight physical exertion, even when I'm in peak physical shape (I've been this way my entire life), so anything that reduces redness and heat is something I'll pretty much instantly try. I already use several other Coola products (their hair sunscreen is amazing) so this was interesting right away. After going on a brisk walk pushing the stroller (while pregnant by the way), I tried this spray on my face and chest. It was genuinely refreshing immediately! It didn't bother my skin, was a good amount of product in one spray, and didn't have any kind of weird smell. Honestly for $20, I would buy this repeatedly every spring/summer, especially in the Midwest! I'm considering ordering an extra bottle just for my daughter to take with her to summer camp. Pro tip: store in the fridge for even more refreshing-ness!
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Reviewed in the United States on April 17, 2026
A
Amazon Customer
Birmingham, US
★★★★★ 4
Amazing ability to calm red, itchy skin but pricier than alternatives
When I saw this product, I was a bit skeptical. I have extremely dry skin that’s prone to red, itchy spots but it seemed unlikely a misty spray would be anywhere near as beneficial as the creams and ointments I’ve turned to over the years. Since I’ve used other COOLA products and really liked them, I decided to give it a try and I was pleasantly surprised. I tried it on a couple of red patches on my face. There’s an immediate feeling of cooling relief (which leads me to believe this would also be a great solution for a burn), but what I found amazing was the redness decreased significantly and immediately. After a few minutes, I was able to put on makeup, forgoing concealer on those spots. I also tried it on a red, itchy spot on my leg, again calming the itch and decreasing the redness. Just because it seemed unwise to start using hypochlorous acid, the active ingredient in this spray, knowing nothing about it, I did a bit of online research. Apparently, not only is it considered safe and recommended by dermatologists for eczema like conditions, it also is antibacterial and can be used to keep cuts clean and help them heal. I’m sold on the concept of this spray. My one hesitation is that it seems to be more expensive than other similar options – particularly when you do the math to determine cost per ounce. I am a real fan of the COOLA brand, but given that my skin is such that I’ll probably use this regularly, the cost differential may become prohibitive. I would highly recommend this product for anyone who wants it on hand for the occasional sunburn or blemish. For those like me who would benefit by using it once or more per day, while still singing its praises as to efficacy, I would have to qualify the recommendation due to price.
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Reviewed in the United States on March 4, 2026
J
Jason
West Palm Beach, US
★★★★★ 5
Refreshing, Recovery Mist
I’ve been using this COOLA Recovery+ Face Mist right after running, and it does wonders. After a run, my face usually looks flushed and feels a bit irritated from sweat and heat. A couple sprays of this helps tremendously. It provides an immediate cooling and refreshing feel without irritation. It really helps reduce that post run redness faster and it feels very gentle. It’s super easy to use. You just spray it on and let it dry.
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Reviewed in the United States on April 23, 2026
M
Verified Purchase
Marcia Staley Olsen
Houston, US
★★★★★ 5
Good quality
light and blends pretty well
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Reviewed in the United States on February 6, 2026
H
Verified Purchase
Hunter
Birmingham, US
★★★★★ 5
Amazing stuff!!
Love love love this stuff! You do have to spread it out well to not go right through it but it doesn’t take more than a thin layer to protect you all day!!
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Reviewed in the United States on October 15, 2025

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