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Description
Cycloastragenol - 10 mg, 30 capsulesCycloastragenol is a bioactive molecule derived from Astragalus, a botanical widely used in Traditional Chinese Medicine and prized for its adaptogenic, immune supporting, and whole body benefits. Emerging evidence suggests cycloastragenol may unlock key aspects of healthy aging; it is known to support: Telomerase activation* Healthy telomere length* Healthy DNA structure* Antioxidant activity* Optimized aging at the genetic level* View Certificate of
Cycloastragenol is a bioactive molecule derived from Astragalus, a botanical widely used in Traditional Chinese Medicine and prized for its adaptogenic, immune-supporting, and whole-body benefits. Emerging evidence suggests cycloastragenol may unlock key aspects of healthy aging; it is known to support:
- Telomerase activation*
- Healthy telomere length*
- Healthy DNA structure*
- Antioxidant activity*
- Optimized aging at the genetic level*
Research-Supported Benefits:
Supports telomere length and healthy aging. Telomere attrition is one of the hallmarks of aging. Telomeres are the protective caps of chromosomes and help protect them from degradation. Critically short telomeres have been associated with cellular senescence and other parts of the aging process. Cycloastragenol may help activate telomerase, the major enzyme responsible for maintaining telomere length.*Supports healthy cell cleanup and antioxidative status. Improvement in markers related to antioxidative status was observed in the presence of cycloastragenol in an animal study. Cycloastragenol was also shown to help support the elimination of senescent cells in another animal study.*
References:
Ikram M, Jo MH, Choe K, et al. Cells. 2021;10(10):2719.
Ip FCF, Ng YP, An HJ, et al. Neurosignals. 2014;22(1):52-63.
Zhang Y, Gao D, Yuan Y, et al. Int J Mol Sci. 2023;24(7):6554.
- May help activate telomerase, the major enzyme involved in adding back telomeric DNA to the ends of chromosomes, by regulating MAPK and Akt signaling pathways.*
- May help support cAMP response element binding (CREB) activation.* CREB helps regulate gene expression related to cell survival and replication in many cell types.
- May support antioxidant activity in the aging brain.*
| Supplement Facts | ||
|---|---|---|
| Serving Size: 1 Capsule |
||
| Servings Per Container: 30 |
||
| Amount Per Serving | %DV | |
| Cycloastragenol (from Astragalus membranaceus Extract) (root) |
10 mg | † |
| † Daily Value not established | ||
REV.06.24
- OTHER INGREDIENTS: Vegetable capsule, rice flour.
- DOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, fish, shellfish, tree nuts, peanuts, sesame.
- SUGGESTED DAILY USE: Take one (1) capsule per day, or as directed by your healthcare professional.
-
NOTE: Store in a cool, dry place, away from direct sunlight. Do not use if tamper evident seal is broken or missing. KEEP OUT OF REACH OF CHILDREN.
-
CAUTION: Not intended for use if you are pregnant or nursing. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.
- Superior Absorption and Bioavailability. A pharmacokinetic study showed that cycloastragenol has superior absorption and bioavailability compared to astragaloside IV, the main active constituent in A. membranaceus. This is in part due to cycloastragenol's low molecular weight.
- Science-First Formulations: We source only the highest quality ingredients backed by validated research to help you achieve your longevity goals.
- Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.
- Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.
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Product Reviews
★★★★★ 5
Ergonomic good, material so, so
Size: Large, Color: Wishbone
Nice ergonomic, but the plastic come off and dog chew it. I had rather have a stronger material adequate for bigger dogs.
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Reviewed in the United States on April 30, 2026
★★★★★ 3
Love it, nice for tough chewers, split in half during play
Size: X-Large, Color: Textured Ring, Size: X-Large, Color: Textured Ring
LOVE THIS PRODUCT, would’ve gotten 5 stars but i threw it for my dog and it split in half on contact with the floor. It had lasted us well over 5 months, it’s not his favorite toy but he’ll pick it sometimes, i wouldn’t say it’s unsafe in half just don’t give the smaller parts!
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Reviewed in the United States on December 18, 2025
★★★★★ 5
Dogs love them
Size: X-Large, Color: Textured Ring
Great for aggressive chewers . hold up well
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Reviewed in the United States on April 26, 2026
★★★★★ 5
Great for power chewers
Size: Large, Color: Bundle
Nothing beats Nylabone!!! Our lab has destroyed everything else… even the extra durable black kongs. Finally a chew toy that is super durable and great size.
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Reviewed in the United States on June 12, 2026
★★★★★ 5
Dogs love them
Color: GT-2P
I have 5 large dogs and they love their chew toys but are picky and tend to tear up the ones they like. These large bones are perfect for my 70 - 90 pounds dogs and are almost indestructible. Most chew toys last a day with them these have lasted a couple of weeks and show no sign of being destroyed anytime soon.
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Reviewed in the United States on June 11, 2026