SKU: 51280639929

MTHFR & BHMT Assist

$48.60 $54.00
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Ships within 48 hours · Estimated delivery Jul 12 - Jul 17

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Description

MTHFR & BHMT AssistDescription: MTHFR & BHMT Assist is designed to support the MTHFR variants when the individual needs less methylation support, possibly due to the CBS, COMT, and MAO variants. It can also be used when undermethylation is suspected or is found on laboratory assessment, but only a small amount of support is needed or can be tolerated. This product also contains the non methylated form of vitamin B12, hydroxocobalamin, a smaller amount of

Description:

MTHFR & BHMT Assist is designed to support the MTHFR variants when the individual needs less methylation support, possibly due to the CBS, COMT, and MAO variants. It can also be used when undermethylation is suspected or is found on laboratory assessment, but only a small amount of support is needed or can be tolerated. This product also contains the non-methylated form of vitamin B12, hydroxocobalamin, a smaller amount of Trimethylglycine (TMG), less B6 (to stimulate CBS less) than compared with MTHFR, MTR, MTRR & BHMT ASSIST. It also contains phosphatidylserine and phosphatidylcholine to support BHMT and a small amount of niacin to reduce methyl groups. This unique “low dose” methyl support is gentle and highly effective in supporting various metabolic pathways.

This product contains stomach and duodenal tissue to help aide absorption. These are PORCINE-based tissues, not bovine-based (from pork, not beef - so those with pork allergies should beware).

Learn more about MTHFR mutations here. 

Ingredients:

  • Vitamin B1
  • Vitamin B2
  • Niacin
  • Vitamin B6
  • Folate
  • Vitamin B12
  • Biotin
  • Magnesium
  • Zinc
  • TMG Betaine
  • Stomach Tissue
  • Lecithin
  • Duodenal Substance
  • Pancreatin
  • Intrinsic Factor
  • Lithium Orotate

Sugar free, salt free, starch free, wheat free, soy free, yeast free, gluten free, no milk derivatives, no artificial colors or flavors, preservative free

Potential Benefits:

  • assists with over-methylation issues
  • helps reduce methyl groups

 

Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.

 

 

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 51280639929

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4.3 ★★★★★
Based on 1719 reviews
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Product Reviews
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Verified Purchase
Niki Picks
New York, US
★★★★★ 5
Gentle cleanser for dry and sensitive skin.
Style: Tolerance Daily Foaming Facial Cleanser, Style: Tolerance Daily Foaming Facial Cleanser
I have dry and sensitive skin, and this cleanser has worked very well for me. It is very gentle on the skin and has not caused any irritation. The texture is light and foamy, it spreads easily across the face and rinses off without leaving any residue. After using it, my skin feels clean, soft, and comfortable, without any tightness. The size is quite large, which I find great because it lasts a long time with daily use. Overall, a simple but very pleasant cleanser for sensitive skin.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 13, 2026
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Verified Purchase
Elizabeth Browning
Alexandria, US
★★★★★ 5
I Just Want to Help People With Skin Problems!
Style: Tolerance Control Soothing Skin Recovery Cream
I so wish I had known about this skincare line a long time ago, but just glad I did find it at all. I have rosacea (including ocular rosacea) diagnosed by a dermatologist. I had been through all the typical stores and websites, trying so many things over the last 15 years. Yes, most were supposed to be for people with skin problems. EVERY SINGLE TIME I tried something, within five minutes, my skin was bright red. My skin reacted to EVERYTHING. I started to believe there was not one single product on the entire planet that my skin would not react to! It was so frustrating. Purchase, fail, repeat. Thing is, I had tried their spring water spray. I sort of ignored all the other products until I was talking to someone randomly and they asked if I had tried Avene. Honestly I decided maybe this was providence and that I had better try it just to be on the safe side. What would life be like if I had ignored their advice and not tried it? If this company ever goes out of business, I will have to live with terrible skin because I already know there is nothing else out there. I had read a review whereby someone said their doctor told them the longer they used the products, the better their skin would get. This is completely true. But even initially, all I cared was that I could relieve the dryness with SOMETHING that did not turn my skin RED IMMEDIATELY! Even THAT, I would have been happy with! Now for the rest of the benefits. I had the good intuition to purchase two of these when they were on sale. I am so glad I did. I use it like crazy every chance I get. It just feels so good going on and I like touching my skin even after the product dissipates. No redness, no irritation, it actually CALMS my skin. And makes it like, well, "real skin." I'm glad I also got the thicker version in the tube, Cicalfate. This is my go-to for dryer areas and in the winter. The two together along with the water spray, if you like to use something like that, are a great overall program. Definitely other things I would like to try. Again, my goal was to help others who have skin problems because everything else out there has no concept whatsoever of calming the skin, but the exact opposite -- irritating it worse (even if those products are supposed to help with redness or irritation). And I felt the company truly deserves a shout-out because they GET IT when it comes to skincare products. Whatever they've done, they are experts, far more than all the other skincare lines and I don't care how long those have been around. If it doesn't immediately tell you your skin "likes it" and shows it by not reacting or immediately getting better, why on earth would you pay your hard-earned money to buy it and keep using it? It's worth every penny, don't bat an eyelash, your skin is worth that and more. If it's on sale, get a lot of it because trust me, you are going to want and need it. You will be so glad you got more than one. I definitely am! THANK YOU, AVENE, WE LOVE YOU HERE IN AMERICA! YOU UNDERSTAND SKINCARE LIKE NO OTHER COMPANY! Update: Wanted to comment that I'm still so grateful for a product that does FAR MORE than what you expect! I recently bought more. I watch my skin calm down the minute I put it on. I don't know entirely how the ingredients do what they do, but to the company ... please don't fix what isn't broken! Too many companies have a good thing and then change it. Please don't, the products are perfect and far beyond expectation! I also wanted to mention it seems the Tolerance tube will get EVERY LAST BIT out, you won't be wondering if there is anything left you are discarding. The Cicalfate tube is a bit different, it's more like a squeeze tube. But I feel I can still get the product out to use it all. That said, you get your money's worth. I'm also starting to use the Cicalfate on my hands in the winter, too (which are sadly starting to show my age). But this product line has literally CHANGED MY LIFE! BUY IT, it's the REAL DEAL!
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Reviewed in the United States on August 10, 2025
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Verified Purchase
Jeanie
Bozeman, US
★★★★★ 5
Love this cream
Style: Tolerance Control Soothing Skin Recovery Cream
I absolutely love the Avène Tolerance Control Soothing Skin Recovery Cream — it’s become a sanctuary for my sensitive skin. From the very first application, I noticed how calming and gentle it feels. The texture is rich yet lightweight, absorbing beautifully without any greasiness. This cream has been a game‑changer for days when my skin feels irritated, reactive, or overwhelmed. It instantly soothes redness and discomfort, and over time my skin feels stronger, more balanced, and resilient. What really stands out is how comfortable and nourished my skin feels all day long — no tightness, no irritation, just pure relief.
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Reviewed in the United States on February 26, 2026
T
Verified Purchase
Tiffany
Natrona Heights, US
★★★★★ 5
Must have for rosacea sensitive skin!
Style: Tolerance Control Soothing Skin Recovery Cream
I have fair, sensitive skin & since being in peri-menopause I suddenly have rosacea. This cream is SO gentle on the skin but so instantly calming. It hydrates so well & a little goes a long way. I will be buying this over & over from now on!
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Reviewed in the United States on April 15, 2026
A
Verified Purchase
Amazon Customer
Grantham, US
★★★★★ 5
Great for Sensitive Skin
Style: Tolerance Control Soothing Skin Recovery Cream
I have very sensitive skin and have tried everything to try and prevent rosacea flairs. I recently came across this brand and I absolutely love this recover cream. I consider this now the holy Grail for Rosacea and sensitive skin. It makes my skin feel hydrated and non-reactive. It is soothing and I just cannot get enough of it. It is pricy but it is worth it to not have my face constantly feeling like its burning or irritated.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 2, 2026

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