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Description
Liposomal NMN Pro™ 300 - 60 capsulesHelps combat aging, supports heart health and promotes muscle strength and cognition NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health and body weight. Nicotinamide mononucleotide (NMN) is a derivative of the B vitamin niacin that may improves health and longevity by serving as a precursor to NAD+. Liposomal form of NMN allows for increased
Helps combat aging, supports heart health and promotes muscle strength and cognition
- NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health and body weight.
- Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that may improves health and longevity by serving as a precursor to NAD+.
- Liposomal form of NMN allows for increased bioavailability and enhanced absorption.
Research-Supported Benefits:
Supports Longevity. Studies have shown that boosting NAD+ synthesis in the body extends the lifespan of yeast, worms and flies. (1)Blood Sugar Regulation. As we age, we have more trouble processing glucose, leading to higher blood sugar—a known contributor to several metabolic-related disorders. Supplemental NMN has been shown to improve several markers of skeletal muscle glucose metabolism that are commonly dysregulated in people with metabolic disorders. (2)
Supports Metabolism and Healthy Weight. Although excessive body weight can develop at any age, adults over age 40 are particularly susceptible to age-related weight gain as metabolism slows down and body composition is altered to favor fat over lean muscle. As obese individuals have reductions in both NAD+ levels and ATP (energy) production, replenishing NAD+ through NMN can help to reverse this while improving metabolic pathways to maintain a healthy weight. (3,4,5)
Supports Healthy Cognition: Declining cognitive function with age is related to a reduced NAD+ levels that impair mitochondrial function. Replenishing NAD+ stores through NMN may be able to prevent this dysfunction. (6,7,8,9)
Supports Healthy Skin: In our 30s and 40s, the appearance of our skin can start to show signs of age. Several studies have examined how boosting NAD+ levels in the skin (10, 11)
References
1. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016/j.cmet.2016.09.004
2. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126/science.abe9985
3. Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022;14(4):755. Published 2022 Feb 11. doi:10.3390/nu14040755
4. Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021;18(1):54. Published 2021 Jul 8. doi:10.1186/s12970-021-00442
5. Yoshino J, Mills KF, Yoon MJ, Imai S. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528-536. doi:10.1016/j.cmet.2011.08.014
6. Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016/j.cmet.2016.09.013
7. Tarantini S, Valcarcel-Ares MN, Toth P, et al. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019;24:101192. doi:10.1016/j.redox.2019.101192
8. Kiss T, Nyúl-Tóth Á, Balasubramanian P, et al. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020;42(2):527-546. doi:10.1007/s11357-020-00165-5
9. Wang X, Hu X, Yang Y, Takata T, Sakurai T. Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death. Brain Res. 2016;1643:1-9. doi:10.1016/j.brainres.2016.04.060
10. Katayoshi T, Nakajo T, Tsuji-Naito K. Restoring NAD+ by NAMPT is essential for the SIRT1/p53-mediated survival of UVA- and UVB-irradiated epidermal keratinocytes. J Photochem Photobiol B. 2021;221:112238. doi:10.1016/j.jphotobiol.2021.112238
11. Feng Z, Qin Y, Huo F, et al. NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury. Biochim Biophys Acta Mol Basis Dis. 2022;1868(1):166287. doi:10.1016/j.bbadis.2021.166287
12. Gopi S, Balakrishnan P. Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. J Liposome Res. 2021;31(4):356-364. doi:10.1080/08982104.2020.1820521
| Supplement Facts | ||
|---|---|---|
| Serving Size: 2 Capsules | ||
| Servings Per Container: 30 | ||
| Amount Per Serving | %DV | |
| Uthever® β-Nicotinamide Mononucleotide (NMN) | 300 mg | † |
| † Daily Value (DV) not established | ||
Uthever® is a registered trademark of Eepharm (Shanghai) Co., Ltd.
REV.06.25
- OTHER INGREDIENTS: Sunflower lecithin, microcrystalline cellulose, hypromellose (capsule).
-
SUGGESTED DAILY USE: Take two (2) capsules per day, with or without food, preferably in the morning.
- CAUTION: Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place.
- Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that may improve health and longevity by serving as a precursor to NAD+.
- NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health and body weight.
- ProHealth’s Liposomal NMN features an innovative delivery system that may help to increase the product's bioavailability (how well it’s absorbed and used by the body).
- Only Clinically-Proven NMN. ProHealth’s NMN is the only clinically-proven NMN to boost NAD+ levels in a peer-reviewed, double-blind, placebo-controlled, published clinical study. Results of the study indicated a 38% increase in NAD+ levels and a 12-year reversal in biological age. (12)
- Unique Liposomal Delivery Method. ProHealth’s Liposomal NMN features an innovative delivery system that may help to increase the product's bioavailability (how well it’s absorbed and used by the body).
- Liposomes are nano-sized bubbles with a unique molecular structure that acts as a delivery vehicle to facilitate the transport of NMN into our cells.
- The double-layered bubble safely protects the compound inside, allowing it to travel through the harsh digestive tract and bloodstream until it meets our cells. From there, the liposome merges with our cell membranes and releases the inner nutrient contents into the cell.
- The body recognizes and accepts liposomal structures because they are phospholipid-based, mimicking our own cell membranes. This means compounds can be directly delivered into cells.
- Convenient Capsule Form. This liposomal NMN comes in capsule form, making it easy and convenient to take NMN while on the go or traveling.
- Solvent-Free. Compared to other NMN products, ours is made without any chemical solvents.
- Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.
- Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.
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- We offer a 30-day return/exchange service after receiving.
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4.8 ★★★★★
Based on 2062 reviews
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Product Reviews
★★★★★ 5
Great mouse
Size: 1 Pack, Style: USB Receiver, Color: Swift Grey
It synced right up and is working great
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Reviewed in the United States on June 7, 2026
★★★★★ 5
Basic mouse that works - - for now.
Size: 1 Pack, Style: USB Receiver, Color: Blue
I ordered this mouse (in blue) to replace the recently deceased exact same model that I've used for the past 2 or 3 years. I like the simplicity of the M185 mouse and mostly the best bang for your buck! I caught this one on sale for less than a ten-spot, so I thought, "why not."
I'm hoping that this one will last a bit longer than my two previous M185 models, that averaged about 3 years each. This model seems plagued by a short life span and is predisposed to mysteriously and suddenly dying, without any obvious symptoms or warning of any kind - - you're working and clicking along, going about your day, when suddenly the cursor on the computer screen freezes and that's it. Nothing, zero, nada. Funny thing, I'm very careful not to abuse or drop the mouse, and keep a fresh battery installed and watch for leakage and all that stuff - - they just stop working, and I assume it is caused by some sort of inherent electronic fault in the circuitry of the previous M185's. Due to my loyalty to the brand and model (and since it was on sale) I decided to give it one more shot. They say that "third time's a charm".
I like the fact that the M185 is simple and uncluttered with extra buttons that I would never use for my purpose, which is simple web-browsing and the occasional text document production. The feel is solid, not heavy, but not cheap feeling, either. I'm used to the shape of this mouse, which to me is quite comfortable for long sessions, another reason why I kind of wanted to stay with this model. The buttons have an audible "click", which doesn't bother me at all, and the wheel moves smoothly and also has a clicking operation (which I rarely ever use). The overall surface of the mouse has a matte finish, but like my previous models I'm sure it will eventually wear shiny spots where my fingers reside and will attain a more "well-used" look in time. Connecting it was a breeze, too. I just plugged the dongle into a spare rear usb port of my desktop, and the mouse connected instantly, no problem. The dongle can be stored safely inside the battery compartment, so you can take the whole thing out of the house if needed for use elsewhere. The speed of 1000 dpi seems just right for my purposes. The one I ordered even came with its own AA Duracell battery, which I wasn't really expecting. This mouse also enters "sleep mode" when you don't use it for a while, and I can't say how many times I've got up and left it on all night. And that's not hard to do, as I'll explain next.
The only real negative to this mouse is the absence of any easily visible status indicator of it's on / off switch. The rear housing of this mouse is matte black, including the tiny switch where you turn it on and off with your fingernail, with only a very faint "on" lettering (also black), and very hard to see with my aging eyes. The laser is not lighted or visible when on, also adding to the confusion, especially in a darkened room. So, as a workaround, I took a tiny drop of green paint and placed it down inside the switch slider to visibly help indicate the "on" position, and likewise a dot of bright orange for the "off" position. Many of Logitech's more expensive models (and a few other manufacturers) include this color-coded switch indication. I guess for the $$, they had to cut corners somewhere - - a minor complaint.
In summary, this is a good basic mouse that works - - let's hope that this one will last longer than its two predecessors.
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Reviewed in the United States on February 17, 2023
★★★★★ 3
Comfortable, but not well laid out and a bit too expensive.
Style: Right-Handed, Pattern Name: Combo, Color: Graphite
I have used a particular brand of keyboards for decades because of their features, comfort, reliability, and functionality. However, I type non-stop at my job and my employer usually just gives me run-of-the-mill equipment to use, so I always buy my own. My typing style will literally eat the keys off after about 2-3 years and 80% of the letters are gone off the keys in less than a year. I tried milking my last setup for an extra amount of time, but it was pretty bad. So I did some shopping for an ergo setup like this. I have a lot of nerve damage from my career choice so these features are important to me and after some shopping I landed on this selection. I will say I do like the feel of the keyboard and even though the mouse takes some adjustment I find it easy to use and very comfortable. So far the keys are holding up well to my abuse. I like the comfort of the wrist rest as well. The only real negatives are the following:
I don't care much for the keyboard layout, the arrow keys are in a goofy spot, and the home end pg up and down keys are in a terrible place as well. It took forever for me to get used to the backspace and delete key locations too. I'm adjusting okay but it has not been super easy. Also, I don't like the position of the function keys to activate the other operations mapped to the F keys. Their selection for what these functions are is not for someone in business. It seems that it is for a teenager. An emoji key? Seriously?
The media keys are pointless as there is no forward or back skip feature and it takes both hands to use them . You have to take your eyes of what you are doing and look at the keyboard just to use these features. The function and windows key should be switched in position as well. Being a PC and not a Mac person may be one of my issues because I don't like the labeling of "start/opt" A feature of this particular unit is sometimes helpful and sometimes not. It seems to have an overactive "enter" key function. Randomly, it hits enter without any input from me. Granted I have a lot of papers flying around but it can happen at inopportune moments, costing me extra keystrokes to undo what was done by this issue. Sometimes it is helpful but I prefer to be in control of what my keyboard is doing and not the other way around. I do like the action of the keys and the comfort, like I said more of my issues are related to specifically how I use it. I have not had any connection issues, battery issues, or any other technical issues. It appears to be fairly reliable and accurate. The last thing I would say is that this setup really seems overpriced. Not sure what that is about but if I had paid for it rather than my employer I would not consider it worth what I paid. With the pluses and minuses I would rate this as a decent purchase but not an ideal piece of equipment for my specific use.
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Reviewed in the United States on April 20, 2026
★★★★★ 4
Vast improvement over traditional mice
Style: Left-Handed, Pattern Name: Mouse, Color: Graphite
This review is primarily for the left handed version. When Logitech introduced the left handed Mouseman in 1991, it was the first and only ergonomic mouse for left handers. Merchants refused to dedicate shelf space to it, so it was short lived.
The latest version is leaps and bounds above the original and is the most comfortable and natural feeling mouse that I've ever used. At first, it was awkward to use. After about 20 seconds, it felt natural, and traditional mice started feeling very awkward. This mouse lets you keep your arm and wrist in a natural position, whether you are using it as a desk mouse or a couch mouse.
The primary button is the index finger button, whether you use the left or right handed version. The Logitech software doesn't have a true setting for swapping buttons, and uses the Windows setting. So if you had your buttons swapped for your old mouse, you need to unswap them. It also means that your old mouse becomes a right handed mouse on that computer. There's no way of having both set to left handed.
There's a switch to change the sensitivity. The normal one lets you do work needing fine movements, such as drawing programs. The other setting makes it more sensitive to movement, which means more mouse movement with less hand movement. It's also a good feature if you have limited desk space or are using an airplane tray. This lets you avoid having to use the setup screens to change sensitivity.
The scroll wheel is smooth and accurate. It also works for horizontal scrolling if used in conjunction with one of the buttons on the thumb side. It takes getting used to, and is still awkward for me. Those buttons are forward and back buttons by default, so don't use it while editing something on a web page until you are used to it, or you could end up losing everything. A problem is that their Logi software doesn't let you set the scroll increment. It can be done with the Windows mouse settings, but you shouldn't have to go two places to set what the mouse does. Pressing the middle button changes from moving the pointer up and down to scrolling the page up and down. Unfortunately, there's no speed adjustment. The round symbol that pops up should really be a longer vertical symbol that allows greater control over speed.
The mouse includes a Logibolt receiver that can plug into a USB port, or you can use the mouse directly with your computer's Bluetooth if it meets the specs.
If you use it with your computer's Bluetooth, you remove the tab from the mouse so the battery connects, and then use your computer's Bluetooth configuration. That will save you a USB port. If you need to use the mouse to set up Bluetooth, use the receiver, and then store it inside the mouse once you have your computer's Bluetooth set up.
If you use the receiver, plug it into a USB port first, then pull the tab. If you want to be able to use both, there's a button on the bottom to let you set it for up to three different devices. So if it's set for your computer's Bluetooth, and want to set up the receiver to use on another computer, plug in the receiver, touch the button on the bottom of the mouse (the light will move from 1 to 2) and you will be paired. You can also use the third setting for another device. If you paired it to both using the same computer, you can unplug the receiver and use the button to go back to setting 1.
If you have a desktop computer, you will want to have the receiver paired, and can use it if you need to change a bios setting, since Windows won't be loaded. So it's good to pair it, even if you will just store it inside the mouse. It would be good to pair it anyway with any computer, so it's ready to go if you ever need it.
There's no instruction manual included, nor do they give you a link to one in the configuration software. The QR code takes you to the software download page, but doesn't give a link to the online manual. So some of this wasn't clear to me without searching online. Their original Mouseman came with a 148 page manual and a 48 page getting started guide. The new one comes with pictorial printed on the cardboard it's wrapped in. Something in between might have been nice, even if it were just a link to the manual.
Update: 18 months later, it's still working well but the battery is down to 5%. I'm changing the battery.
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Reviewed in the United States on November 14, 2022
★★★★★ 5
My favorite mouse ever
Style: Right-Handed, Pattern Name: Mouse, Color: Off White
I'm very particular when it comes to mice. It has to be:
- quiet click and scroll
- scroll wheel, not track ball
- bluetooth
- vertical
- real battery, NOT rechargeable
There are actually several mice that fit all those criteria, and I've tried nearly all. This Logitech is double the price of most of the others, but for me well worth it. Prior to this I used the Mojo which is about half the price, and that mouse is probably my 2nd favorite but it is a distant second. Compared to the Mojo and others, this mouse has more precise movement, smoother scrolling, and more reliable clicks. Because of the vertical orientation, my finger tends to click diagonally downward with gravity instead of fully horizontal in line with the intended click direction. That causes the Mojo to sometimes miss my clicks, forcing me to constrain my finger direction more carefully, often requiring several tries just to click something. But this Logitech has no such issue, it's very responsive every time even with my sloppy clicks.
So while I used to think the Mojo was the best I could find given my requirements, this Logitech is clearly better. When I spend all day at the computer, these minor things make a big difference to me, therefore well worth the extra money.
Also want to mention I'm 6' 4" tall and the size of this mouse is fine for me. It is a little smaller than some others, but it feels fine in my hand, it's not abnormally tiny or anything. I was concerned because the description says it's intended for smaller hands and suggested I should get their larger MX Vertical model instead. I would have considered it but the MX Vertical has a rechargeable battery which is a deal-breaker for me. What's my beef with rechargeable batteries? Earlier I had the Seenda vertical mouse but its rechargeable battery died after a year, unable to recharge, so I figured it was a fluke and bought another, and same thing happened after a few months. So after that I switched to replaceable batteries and never looked back. Replaceable batteries last forever (well, they only last a year too, but then you just replace the battery!). I've been very happy using replaceable batteries, way more reliable and durable, because all rechargeables die eventually, and it is easier to replace a battery than an entire mouse!
So in summary, if you're price sensitive you could get a usable vertical mouse for less. But if you're OK to spend a little more for a tool you might well use all day for years, then this one is totally worth it IMO.
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Reviewed in the United States on March 27, 2025
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