SKU: 13839127880

Aminated Prussian Blue Nanoparticles

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Description

Aminated Prussian Blue NanoparticlesProduct Name Name: a>Aminated Prussian Blue Nanoparticles Product Overview Prussian Blue (PB for short), also known as Teng's Blue or Ferrocyanide, is a polymeric complex composed of three elements: C, N, and Fe. It generally refers to Ferrocyanide, and its molecular formula is Fe4 [Fe (CN) 6] 3. PB can be used as an antidote for the treatment of thallium and cesium poisoning, and has good biological safety. PB is synthesized by aging crystallization

Product Name

Name:a>Aminated Prussian Blue Nanoparticles

Product Overview

Prussian Blue (PB for short), also known as Teng's Blue or Ferrocyanide, is a polymeric complex composed of three elements: C, N, and Fe. It generally refers to Ferrocyanide, and its molecular formula is Fe4 [Fe (CN) 6] 3. PB can be used as an antidote for the treatment of thallium and cesium poisoning, and has good biological safety.

PB is synthesized by aging crystallization of potassium ferrocyanide and polyvinylpyrrolidone (PVP). The reaction mainly involves the coordination of CN bonds in potassium ferrocyanide with Fe3+and Fe2+to form crystal nuclei, while PVP is doped with its own CN bonds to form a crystalline structure. Hollow mesoporous Prussian blue (HMPB) is prepared by etching PB with hydrochloric acid, and the cavity structure can be used to load drugs to improve tumor treatment efficiency.

Technical Parameter

Particle size: 50nm-70nm

Characteristicc absorption peak: ~700 nm   

Density:1mg/mL

Product Features

1. Good dispersibility: The raw material PVP, as an amphiphilic substance, is easily soluble in water, resulting in PB with good water dispersibility.

2. Good drug loading capacity: The hollow mesoporous structure obtained by etching of this product has a large surface area and pore volume, which can be used as a nanocarrier to load small molecular substances such as drugs and genes, meeting different biomedical needs.

3. Multiple nano enzyme activities: PB has POD enzyme activity and can decompose H2O2 to produce hydroxyl radicals (· OH); Has SOD enzyme activity and can catalyze the production of H2O2 and O2 from peroxyl groups (· OOH); It has CAT activity and can decompose H2O2 to produce O2.

4. Excellent photothermal conversion efficiency: PB has good light absorption ability at 808 nm, which can convert light energy into heat energy. The generated heat can ablate tumor cells, and the increase in temperature can also enhance nanoenzyme activity.

Application Fields

1. Drug loading: PB, due to its unique hollow mesoporous structure, can load chemotherapy drugs, improve drug loading rate, and achieve targeted drug delivery through surface modification of targeted molecules, thereby improving therapeutic efficacy and slowing down drug side effects on normal cells.

2. Photothermal therapy: PB, due to its special lattice structure, has near-infrared light absorption characteristics and biological safety, and has been widely studied as a new type of photothermal conversion material in the application of tumor ablation.

3. Nanoenzyme therapy: PB has various nanoenzyme activities, such as POD, SOD, CAT enzyme activities, which can clear free radicals, slow down inflammation, alleviate oxidative stress reactions, catalyze hydrogen peroxide to produce oxygen, and alleviate tumor hypoxia.

4. Biomedical imaging: PBNPs have good magnetic resonance imaging (MRI) and photoacoustic imaging (PA) characteristics. At the same time, due to the advantages of their mesoporous structure and surface modification, fluorescence imaging and ultrasound imaging based on PB structure have also been synergistically used for disease diagnosis, leveraging the advantages of multimodal imaging.

Related Information

Please e-mail for the detailed characterization data.

E-mail:[email protected]

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SKU: 13839127880

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B. Mulder
Birmingham, US
★★★★★ 5
Worked well near the equator
Style: SPF 50
I bought this product because I was going to be in the field for a month, outside, every day, all day, in Tanzania at high altitude. A severe sunburn would be hard to treat in the remote area we were in, but also I am very careful about protecting my skin from aging. I had to have mineral based sunscreen because as a whitewater kayaker I know it’s the only truly water resistant kind and it was going to be sweaty. And since I knew I was going to be putting it on every day, and we didn’t have running water in the field (bucket showers only) I didn’t want it to feel gross. (I really wanted to try the spray but I didn’t want to put anything pressurized in my luggage.) And I had already discovered the Coola face sunscreen (30spf version) which had impressed me with how silky smooth and not greasy it is. Now this IS greasier because it is a higher SPF. BUT I think this product is as good as you’re going to get with the protection you’re getting. Like I said, I’m a white water tiger, so I have used a LOT of mineral sunscreens. This was hands down the most comfortable one I’ve used. And it was effective. I didn’t burn once—only time I did burn was when I forgot to put it on one day toward the end of the trip, when we were out for just a couple hours—and I got the first 2nd degree burn I’ve ever had in my life. That was what this stuff had protected me from, all day every day, the entire trip. I did tan a little but I think that was mostly from the few times I was not covered during short bouts or it was cloudy. For my face I used the Coola 50spf face product.
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Reviewed in the United States on August 7, 2022
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SavanahClark
Fort Morgan, US
★★★★★ 5
Love this stuff!
Style: SPF 50
I use this every day and I love how it is frangrance free and creamy. I have a very fair complexion and I will say it leaves a slight white cast but it doesn’t bother me because it almost makes my fairness more creamy looking. My skin texture has improved since wearing it daily and no allergies from it. I highly recommend especially if you have fairer skin otherwise it may leave a cast .
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Reviewed in the United States on February 19, 2023
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Dawn
Lake Worth, US
★★★★★ 5
Excellent mineral sunscreen with minimal white cast.
Style: SPF 50
This is one of the healthier sunscreens I’ve found so far. You’re not likely going to find a mineral sunscreen that doesn’t leave some white cast. However, this one rubs in pretty good with minimal cast. You can dab on and rub in fairly easily… as long as you don’t use too much the white cast should be minimal. I am not sure how well this would work on darker skin tones. My arms are a medium skin tone… my legs are more of a light-medium tone. I prefer mineral sunscreens, and this is the best one I found so far and compatible to Supergoop mineral play. If you liked that one, you would likely enjoy this Coola one too.
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Reviewed in the United States on January 25, 2025
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Kaitlyn Jacobson
Lexington, US
★★★★★ 1
Would not recommend
Style: SPF 50
I literally never write reviews but felt compelled to write one for this sunscreen because I was very caught off guard by all the positive reviews. This sunscreen leaves the most insane white sheen that never soaks in and gets on EVERYTHING. I put this on and drove to the beach and had sunscreen on my car seat, the steering wheel, the center console, the door, EVERYWHERE! It took forever to clean up and was such a hassle and that was after having let the sunscreen soak into my skin for an hour. Also the sunscreen is really thick and difficult to spread and makes you look ghostly white. Plus, the sunscreen has a really odd odor that reminded me of play dough? That might not be a negative thing for everyone but I found it unpleasant. There are definitely better mineral sunscreens out there. For the price I expected a much better product.
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Reviewed in the United States on June 11, 2025
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John Reid
Chelsea, US
★★★★★ 3
Sticky and white
Style: SPF 50
The sunscreen has a very sticky and thick texture. It will keep you from getting sunburnt, but it will also leave you with a white color.
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Reviewed in the United States on July 22, 2024

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